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Bcl-6 Rabbit mAb

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说明书下载
货号: PL0324
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Bcl-6
应用: WB,IHC,IF,ELISA
反应性 : Human,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 79kD
MW(Observed): 90kD
同种型-Isotype : IgG,Kappa

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆号 : Monoclonal

抗原&靶点信息

特异性 : Endogenous
基因名称 : BCL6
蛋白名称 : B-cell lymphoma 6 protein
别名 : BCL6;BCL5;LAZ3;ZBTB27;ZNF51;B-cell lymphoma 6 protein;BCL-6;B-cell lymphoma 5 protein;BCL-5;Protein LAZ-3;Zinc finger and BTB domain-containing protein 27;Zinc finger protein 51

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015],

细胞定位 : Nucleus .

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