信号通路

联系我们

15392937510

地址:湖北省武汉市江夏区神墩四路 666 号武汉国英种业大厦A栋14F 
邮箱:pinuofei2017@163.com
TEL:15392937510

Bcl-6 (Phospho Ser343) Rabbit pAb

复制产品信息

说明书下载
货号: PF0178
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: Bcl-6
应用: IHC,WB
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 80kD

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:500-2000;IHC 1:50-200
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of Bcl-6 (Phospho Ser343) Rabbit pAb at Human, Mouse
基因名称 : BCL6 BCL5 LAZ3 ZBTB27 ZNF51
蛋白名称 : B-cell lymphoma 6 protein (BCL-6) (B-cell lymphoma 5 protein) (BCL-5) (Protein LAZ-3) (Zinc finger and BTB domain-containing protein 27) (Zinc finger protein 51)
别名 : B-cell lymphoma 6 protein;BCL-6;B-cell lymphoma 5 protein;BCL-5;Protein LAZ-3;Zinc finger and BTB domain-containing protein 27;Zinc finger protein 51;

数据库链接:

Organism

基因 ID

SwissProt

背景:

B-cell CLL/lymphoma 6(BCL6) Homo sapiens The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015],

细胞定位 : Nucleus .

推荐产品

相关文献

留言咨询

留下您想咨询的信息,我们会尽快联系您

提交