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Integrin α6 Monoclonal Antibody

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说明书下载
货号: PH1366
货期: 一周
价格: 100μL/2200
+


靶点: Integrin α6
应用: WB,IF
反应性 : Human,Mouse,Rat,Bovine,Dog,Pig
宿主物种 : Mouse
MW(CalcμLated) : 127kD

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:1000-1:2000;IF 1:100-1:500;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal

抗原&靶点信息

特异性 : Integrin α6 Monoclonal Antibody detects endogenous levels of Integrin α6 protein.
基因名称 : ITGA6
蛋白名称 : Integrin alpha-6
别名 : ITGA6;Integrin alpha-6;CD49 antigen-like family member F;VLA-6;CD antigen CD49f

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

integrin subunit alpha 6(ITGA6) Homo sapiens The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],

细胞定位 : Cell membrane ; Single-pass type I membrane protein . Cell membrane ; Lipid-anchor .

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