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货号: PH0663
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: NFkB p65
应用: IHC,IF
反应性 : Human,Mouse,Rat
宿主物种 : Mouse
MW(Observed): 65kD
隐藏域元素占位
详细信息
修饰-Modification : Acetyl
推荐稀释比 : IHC 1:50-300;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Monoclonal
克隆号 : 5G11
抗原&靶点信息
特异性 : The antibody detects endogenous Acetyl NF kB P65(K314/K315) protein
基因名称 : RELA NFKB3
蛋白名称 : Transcription factor p65
别名 : Transcription factor p65;Nuclear factor NF-kappa-B p65 subunit;Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3;
背景:
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],


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