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Rtn-3 Monoclonal Antibody

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说明书下载
货号: PH1460
货期: 一周
价格: 100μL/2200
+


靶点: Rtn-3
应用: IF,ELISA
反应性 : Human
宿主物种 : Mouse

隐藏域元素占位

详细信息

推荐稀释比 : IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications;
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal

抗原&靶点信息

特异性 : Rtn-3 Monoclonal Antibody detects endogenous levels of Rtn-3 protein.
基因名称 : RTN3
蛋白名称 : Reticulon-3
别名 : RTN3;ASYIP;NSPL2;Reticulon-3;Neuroendocrine-specific protein-like 2;NSP-like protein 2;Neuroendocrine-specific protein-like II;NSP-like protein II;NSPLII

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12. [provided by RefSeq, May 2012],

细胞定位 : Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein .

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