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ULA1 Polyclonal Antibody

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说明书下载
货号: PG7771
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+

所属分类:


靶点: ULA1
应用: WB,ELISA
反应性 : Human,Rat,Mouse
宿主物种 : Rabbit
MW(Observed): 58kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;ELISA 1:5000-20000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : ULA1 Polyclonal Antibody detects endogenous levels of protein.
基因名称 : NAE1 APPBP1 HPP1
蛋白名称 : NEDD8-activating enzyme E1 regulatory subunit (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1) (Amyloid protein-binding protein 1) (Proto-oncogene protein 1)

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位 : Cell membrane . Colocalizes with APP in lipid rafts.

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