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货号: PD3204
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
靶点: TRAF2
应用: WB,IHC,IF,ELISA
反应性 : Human,Rat,Mouse,Bovine
宿主物种 : Rabbit
MW(Observed): 60kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : TRAF2 Polyclonal Antibody detects endogenous levels of TRAF2 protein.
基因名称 : TRAF2
蛋白名称 : TNF receptor-associated factor 2
别名 : TRAF2;TRAP3;TNF receptor-associated factor 2;E3 ubiquitin-protein ligase TRAF2;Tumor necrosis factor type 2 receptor-associated protein 3
背景:
TNF receptor associated factor 2(TRAF2) Homo sapiens The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this pro


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