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货号: PH1517
货期: 一周
价格: 100μL/2200
靶点: OPG
应用: WB,IHC,IF,ELISA
反应性 : Human
宿主物种 : Mouse
MW(CalcμLated) : 46kD
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
抗原&靶点信息
特异性 : OPG Monoclonal Antibody detects endogenous levels of OPG protein.
基因名称 : TNFRSF11B
蛋白名称 : Tumor necrosis factor receptor superfamily member 11B
别名 : TNFRSF11B;OCIF;OPG;Tumor necrosis factor receptor superfamily member 11B;Osteoclastogenesis inhibitory factor;Osteoprotegerin
背景:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008],


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