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货号: PD2485
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
靶点: IL-6Rα
应用: WB,IHC,IF,ELISA
反应性 : Human,Rat
宿主物种 : Rabbit
MW(Observed): 53kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : IHC: 100-300;WB 1:500-1:2000;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : IL-6Rα Polyclonal Antibody detects endogenous levels of IL-6Rα protein.
基因名称 : IL6R
蛋白名称 : Interleukin-6 receptor subunit alpha
别名 : IL6R;Interleukin-6 receptor subunit alpha;IL-6 receptor subunit alpha;IL-6R subunit alpha;IL-6R-alpha;IL-6RA;IL-6R 1;Membrane glycoprotein 80;gp80;CD126
背景:
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011],


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