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IL-1F6 Polyclonal Antibody

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说明书下载
货号: PD2143
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: IL-1F6
应用: IHC,IF,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : The antibody detects endogenous IL-1F6
基因名称 : IL36A FIL1E IL1E IL1F6
蛋白名称 : Interleukin-36 alpha (FIL1 epsilon) (Interleukin-1 epsilon) (IL-1 epsilon) (Interleukin-1 family member 6) (IL-1F6)
别名 : Interleukin-36 alpha;FIL1 epsilon;Interleukin-1 epsilon;IL-1 epsilon;Interleukin-1 family member 6;IL-1F6;

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients. [provided by RefSeq, Nov 2015],

细胞定位 : Cytoplasm . Secreted . The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion. .

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