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推荐稀释比 ： ELISA 1:5000-100000
组成 ： Phosphate-buffered solution
来源 ： Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 ： Recombinant Expression and Affinity purified
储存 ： -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 ： Please check the information on the tube
克隆性 ： Monoclonal
克隆号 ： PN0508
抗原&靶点信息
特异性 ： This recombinant monoclonal antibody can detects endogenous levels of CD27 protein.
基因名称 ： CD27 TNFRSF7
蛋白名称 ： Cytokine receptor common subunit beta (CDw131) (GM-CSF/IL-3/IL-5 receptor common beta subunit) (CD antigen CD131)
别名 ： IL-3R common β chain;CDw131;Beta-C antibody;CD131 antibody;CDw131 antibody;Colony stimulating factor 2 receptor beta antibody;Colony stimulating factor 2 receptor beta low affinity;granulocyte macrophage;antibody;Common beta chain antibody;Csf2rb antibody;Cytokine receptor common beta chain antibody;Cytokine receptor common beta chain precursor;CDw131 antigen;antibody;Cytokine receptor common subunit beta antibody;GM CSF/IL 3/IL 5 receptor common beta chain antibody;GM-CSF/IL-3/IL-5 receptor common beta subunit antibody;granulocyte-macrophage colony-stimulating factor receptor;beta antibody;IL3RB antibody;IL3RB_HUMAN antibody;IL5RB antibody;Interleukin 3 receptor;beta antibody;Interleukin 3 receptor/granulocyte macrophage colony stimulating factor 3 receptor beta;high affinity;antibody;Interleukin 5 receptor;beta antibody;SMDP5 antibody;stimulating factor 3 receptor;beta;high affinity;antibody;
背景：
CD27 molecule(CD27) Homo sapiens The protein encoded byThis gene is a member of the TNF-receptor superfamily.This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis.This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process ofThis receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind toThis receptor and is thought to play an important role in the apoptosis induced byThis receptor. [provided by RefSeq, Jul 2008]
细胞定位 ： Membrane; Single-pass type I membrane protein.
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