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推荐稀释比 ： ELISA 1:5000-100000;Flow Cyt 1-2μg/Test
组成 ： Phosphate-buffered solution
来源 ： Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 ： Recombinant Expression and Affinity purified
储存 ： -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 ： Please check the information on the tube
克隆性 ： Monoclonal
克隆号 ： PN0036
抗原&靶点信息
特异性 ： This recombinant monoclonal antibody can detects endogenous levels of CD62L protein.
基因名称 ： SELL LNHR LYAM1
蛋白名称 ： Low affinity immunoglobulin gamma Fc region receptor III-A (IgG Fc receptor III-A) (CD16-II) (CD16a antigen) (Fc-gamma RIII-alpha) (Fc-gamma RIII) (Fc-gamma RIIIa) (FcRIII) (FcRIIIa) (FcgammaRIIIA) (FcR-10) (IgG Fc receptor III-2) (CD antigen CD16a)
别名 ： CD 16 antibody;CD 16a antibody;CD16 antibody;CD16a antibody;CD16a antigen antibody;CD16B antibody;CD16b antigen antibody;Fc fragment of IgG antibody;Fc fragment of IgG low affinity IIIa receptor;CD16;antibody;Fc fragment of IgG low affinity IIIa receptor antibody;Fc fragment of IgG receptor IIIa antibody;Fc fragment of IgG;low affinity III;receptor;CD16;antibody;Fc fragment of IgG;low affinity III;receptor for;CD16;antibody;Fc fragment of IgG;low affinity IIIa;receptor;CD16;antibody;Fc fragment of IgG;low affinity IIIa;receptor;CD16a;antibody;Fc fragment of IgG;low affinity IIIa;receptor for antibody;Fc fragment of IgG;low affinity IIIb;receptor;CD16b;antibody;Fc fragment of IgG;low affinity IIIb;receptor for;CD16;antibody;Fc gamma R3 antibody;Fc gamma receptor III 2;CD 16;antibody;Fc gamma receptor III A antibody;Fc gamma receptor IIIA antibody;Fc gamma receptor IIIb;CD 16;antibody;Fc gamma RIII alpha antibody;Fc gamma RIII antibody;Fc gamma RIII beta antibody;Fc gamma RIIIa antibody;Fc gamma RIIIb antibody;Fc of IgG antibody;Fc-gamma receptor III2;CD 16;antibody;Fc-gamma receptor III2;CD16;antibody;Fc-gamma receptor IIIb;CD16;antibody;Fc-gamma RIII antibody;Fc-gamma RIII-alpha antibody;Fc-gamma RIIIa antibody;FCG 3 antibody;FCG3 antibody;FCG3A_HUMAN antibody;FCgammaRIIIA antibody;FCGR 3 antibody;FCGR 3A antibody;FCGR3 antibody;FCGR3A antibody;FCGR3A protein antibody;FCGRIII antibody;FCGRIII-2 antibody;FcR 10 antibody;FcR-10 antibody;FcR10 antibody;FcRIII antibody;FcRIIIa antibody;IGFR 3 antibody;IGFR3 antibody;IgG Fc receptor III 1 antibody;IgG Fc receptor III 2 antibody;IgG Fc receptor III-2 antibody;IMD20 antibody;immunoglobulin G Fc receptor III antibody;immunoglobulin G Fc receptor III-2 antibody;Low affinity IIIa receptor antibody;Low affinity immunoglobulin gamma Fc region receptor III A antibody;Low affinity immunoglobulin gamma Fc region receptor III-A antibody;Low affinity immunoglobulin gamma Fc region receptor IIIB antibody;neutrophil-specific antigen NA antibody;
背景：
CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.
细胞定位 ： Cell membrane ; Single-pass type I membrane protein .
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