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CRF-RI Polyclonal Antibody

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说明书下载
货号: PD2525
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: CRF-RI
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 50kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : CRF-RI Polyclonal Antibody detects endogenous levels of CRF-RI protein.
基因名称 : CRHR1
蛋白名称 : Corticotropin-releasing factor receptor 1
别名 : CRHR1;CRFR;CRFR1;CRHR;Corticotropin-releasing factor receptor 1;CRF-R-1;CRF-R1;CRFR-1;Corticotropin-releasing hormone receptor 1;CRH-R-1;CRH-R1

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Naturally-occurring readthrough transcription between this gene and upstream GeneID:147081 results in transcripts that encode isoforms that share similarity with the products of this gene. [provided by RefSeq, Aug 2016],

细胞定位 : Cell membrane; Multi-pass membrane protein. Endosome. Agonist-binding promotes endocytosis.

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