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VR1 rabbit pAb

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说明书下载
货号: PD0228
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: VR1
应用: WB
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 92kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of VR1 at Human, Mouse,Rat
基因名称 : TRPV1 VR1
蛋白名称 : VR1
别名 : Transient receptor potential cation channel subfamily V member 1;TrpV1;Capsaicin receptor;Osm-9-like TRP channel 1;OTRPC1;Vanilloid receptor 1;

数据库链接:

Organism

基因 ID

SwissProt

背景:

transient receptor potential cation channel subfamily V member 1(TRPV1) Homo sapiens Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008],

细胞定位 : Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell projection, dendritic spine membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Mostly, but not exclusively expressed in postsynaptic dendritic spines. .

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