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IGF-IR Monoclonal Antibody

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说明书下载
货号: PH1617
货期: 一周
价格: 100μL/2200
+


靶点: IGF-1R
应用: WB,IHC,IF,ELISA
反应性 : Human
宿主物种 : Mouse
MW(Observed): pro:155kD,recetor beta:95kD

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal

抗原&靶点信息

特异性 : IGF-IR Monoclonal Antibody detects endogenous levels of IGF-IR protein.
基因名称 : IGF1R
蛋白名称 : Insulin-like growth factor 1 receptor
别名 : IGF1R;Insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;IGF-I receptor;CD antigen CD221

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],

细胞定位 : Cell membrane ; Single-pass type I membrane protein .

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