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货号: PH1166
货期: 一周
价格: 100μL/2200
所属分类:
靶点: Keratin(50-60kDa)
应用: WB
反应性 : Human,Mouse,Rat
宿主物种 : Mouse
MW(Observed): 62kD
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
抗原&靶点信息
特异性 : This antibody detects endogenous levels of Keratin(50-60kDa) proteins.
基因名称 : krt5
别名 : 58 kDa cytokeratin;CK 5;CK-5;CK5;Cytokeratin-5;Cytokeratin5;DDD;DDD1;EBS 2;EBS2;epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types;K2C5_HUMAN;K5;Keratin 5;epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types;keratin 5;epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types;Keratin 5;Keratin;keratin complex 2, basic, gene 5;Keratin Type II Cytoskeletal 5;keratin, type II cytoskeletal 5;Keratin-5;Keratin5;KRT 5;KRT 5A;KRT5;KRT5A;type II cytoskeletal 5;Type-II keratin Kb5.
背景:
keratin 5(KRT5) Homo sapiens The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008],


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