信号通路

联系我们

15392937510

地址:湖北省武汉市江夏区神墩四路 666 号武汉国英种业大厦A栋14F 
邮箱:pinuofei2017@163.com
TEL:15392937510

SGK3 Polyclonal Antibody

复制产品信息

说明书下载
货号: PG6843
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: SGK3
应用: WB,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 54kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;ELISA 1:5000-20000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : SGK3 Polyclonal Antibody detects endogenous levels of protein.
基因名称 : SGK3 CISK SGKL
蛋白名称 : Serine/threonine-protein kinase Sgk3
别名 : Serine/threonine-protein kinase Sgk3;Cytokine-independent survival kinase;Serum/glucocorticoid-regulated kinase 3;Serum/glucocorticoid-regulated kinase-like;

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasmic vesicle . Early endosome. Recycling endosome. Endosomal localization is a prerequisite for complete kinase activity. It is essential for its colocalization with the kinase responsible for phosphorylating Ser-486 thus allowing PDPK1 phosphorylation of Thr-320 resulting in complete activation of SGK3. Localized in vesicle-like structures and in the early endosome. Colocalizes with SLC9A3/NHE3 in the recycling endosomes.

推荐产品

相关文献

留言咨询

留下您想咨询的信息,我们会尽快联系您

提交