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PHLP1 Polyclonal Antibody

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说明书下载
货号: PG5791
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+

所属分类:


靶点: PHLP1
应用: WB,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 188kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;ELISA 1:5000-20000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : PHLP1 Polyclonal Antibody detects endogenous levels of protein.
基因名称 : PHLPP1 KIAA0606 PHLPP PLEKHE1 SCOP
蛋白名称 : PH domain leucine-rich repeat-containing protein phosphatase 1 (Pleckstrin homology domain-containing family E member 1) (PH domain-containing family E member 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP)

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

PH domain and leucine rich repeat protein phosphatase 1(PHLPP1) Homo sapiens This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011],

细胞定位 : Cytoplasm. Membrane; Peripheral membrane protein. Nucleus. In colorectal cancer tissue, expression is concentrated at the lateral membrane of epithelial cells.; [Isoform 2]: Cell membrane .

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