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NPRL2 Polyclonal Antibody

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说明书下载
货号: PD2861
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+

所属分类:


靶点: NPRL2
应用: WB,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 43kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : NPRL2 Polyclonal Antibody detects endogenous levels of NPRL2 protein.
基因名称 : NPRL2
蛋白名称 : Nitrogen permease regulator 2-like protein
别名 : NPRL2;TUSC4;Nitrogen permease regulator 2-like protein;NPR2-like protein;Gene 21 protein;G21 protein;Tumor suppressor candidate 4

数据库链接:

Organism

基因 ID

SwissProt

背景:

function:Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.,similarity:Belongs to the NPR2 family.,subunit:Interacts with PDPK1.,tissue specificity:Most abundant in skeletal muscle, followed by brain, liver and pancreas, with lower amounts in lung, kidney, placenta and heart. Expressed in most lung cancer cell lines tested.,

细胞定位 : Lysosome membrane . Localization to lysosomes is amino acid-independent. .

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