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货号: PF0180
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
靶点: Ob-R
应用: IHC,WB
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 132kD
隐藏域元素占位
详细信息
修饰-Modification : Phospho
推荐稀释比 : WB 1:500-2000;IHC 1:50-200
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : This antibody detects endogenous levels of Leptin Receptor (Phospho Tyr986) Rabbit pAb at Human, Mouse,Rat
基因名称 : LEPR DB OBR
蛋白名称 : Leptin receptor (LEP-R) (HuB219) (OB receptor) (OB-R) (CD antigen CD295)
别名 : Leptin receptor;LEP-R;HuB219;OB receptor;OB-R;CD antigen CD295;
背景:
leptin receptor(LEPR) Homo sapiens The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010],


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