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详细信息
推荐稀释比 : ELISA 1:5000-100000
组成 : Phosphate-buffered solution
来源 : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 : Recombinant Expression and Affinity purified
储存 : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 : Please check the information on the tube
克隆性 : Monoclonal
克隆号 : PN0307
抗原&靶点信息
特异性 : This recombinant monoclonal antibody can detects endogenous levels of CD131 protein.
基因名称 : CSF2RB IL3RB IL5RB
蛋白名称 : CD166 antigen (Activated leukocyte cell adhesion molecule) (CD antigen CD166)
别名 : ALCAM;MEMD;CD166 antigen;Activated leukocyte cell adhesion molecule;CD166
背景:
CD131, also known as the IL-3R common β subunit , is a 95-120 kD type I transmembrane glycoprotein and belongs to the Ig superfamily. The common β subunit associates with the specific α subunits of IL-3 receptor, IL-5 receptor and GM-CSF receptor to form high affinity receptors for these cytokines. These cytokine receptors are expressed by neutrophils, eosinophils, monocytes, endothelial cells, fibroblasts and hematopoietic progenitor cells and play a crucial role in growth/activation of eosinophils and in the inflammatory response. The 1C1 antibody is a non-blocking antibody.


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