信号通路

联系我们

15392937510

地址:湖北省武汉市江夏区神墩四路 666 号武汉国英种业大厦A栋14F 
邮箱:pinuofei2017@163.com
TEL:15392937510

RPGF6 Polyclonal Antibody

复制产品信息

说明书下载
货号: PG7566
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: RPGF6
应用: WB,ELISA
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 176kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;ELISA 1:5000-20000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : RPGF6 Polyclonal Antibody detects endogenous levels of protein.
基因名称 : RAPGEF6 PDZGEF2
蛋白名称 : Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2)

数据库链接:

Organism

基因 ID

SwissProt

背景:

function:Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 cyclic nucleotide-binding domain.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 Ras-GEF domain.,subcellular location:Upon binding to M-Ras, it translocates to the plasma membrane.,subunit:Interacts with the second PDZ domain of human PTP1e.,tissue specificity:Isoform 3 has highest expression levels in the brain, heart, liver, lung and placenta and is barely detectable in skeletal muscle, kidney and pancreas.,

细胞定位 : Cytoplasm . Cell membrane . Upon binding to M-Ras, it translocates to the plasma membrane.

推荐产品

相关文献

留言咨询

留下您想咨询的信息,我们会尽快联系您

提交