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SCN8A Polyclonal Antibody

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说明书下载
货号: PG5909
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+

所属分类:


靶点: SCN8A
应用: WB,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 217kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;ELISA 1:5000-20000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : SCN8A Polyclonal Antibody detects endogenous levels of protein.
基因名称 : SCN8A MED
蛋白名称 : Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6)

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010],

细胞定位 : Cell membrane ; Multi-pass membrane protein . Cell projection, axon . Mainly localizes to the axon initial segment. .; [Isoform 5]: Cytoplasmic vesicle. Some vesicles are localized adjacent to melanoma invadopodia and macrophage podosomes. Does not localize to the plasma membrane.

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