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货号: PH1299
货期: 一周
价格: 100μL/2200
所属分类:
靶点: Fatty Acid Synthase
应用: WB,IP,IF
反应性 : Human,Mouse,Rat,Monkey,Bovine
宿主物种 : Mouse
MW(Observed): 273kD
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:1000;ICC 1:400;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
抗原&靶点信息
特异性 : This antibody detects endogenous levels of Fatty Acid Synthase and does not cross-react with related proteins.
基因名称 : fasn
别名 : [Acyl-carrier-protein] S acetyltransferase;[Acyl-carrier-protein] S malonyltransferase;3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase;3-oxoacyl-[acyl-carrier-protein] reductase;3-oxoacyl-[acyl-carrier-protein] synthase;Enoyl-[acyl-carrier-protein]
背景:
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008],


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