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GLYM rabbit pAb

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货号: PD0653
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: GLYM
应用: WB
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(CalcμLated) : 55kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of GLYM at Human
基因名称 : SHMT2
蛋白名称 : GLYM

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],

细胞定位 : Mitochondrion . Mitochondrion matrix, mitochondrion nucleoid . Mitochondrion inner membrane . Cytoplasm . Nucleus . Mainly localizes in the mitochondrion. Also found in the cytoplasm and nucleus as part of the BRISC complex (PubMed:24075985). .

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