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货号: PH1333
货期: 一周
价格: 100μL/2200
所属分类:
靶点: sMtCK
应用: WB
反应性 : Human,Mouse,Rat,Dog,Pig,Rabbit
宿主物种 : Mouse
MW(CalcμLated) : 48kD
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:1000-1:2000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : Affinity purification
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
抗原&靶点信息
特异性 : sMtCK Monoclonal Antibody detects endogenous levels of sMtCK protein.
基因名称 : CKMT2
蛋白名称 : Creatine kinase S-type mitochondrial
别名 : CKMT2;Creatine kinase S-type;mitochondrial;Basic-type mitochondrial creatine kinase;Mib-CK;Sarcomeric mitochondrial creatine kinase;S-MtCK
背景:
creatine kinase, mitochondrial 2(CKMT2) Homo sapiens Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gen


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