信号通路

联系我们

15392937510

地址:湖北省武汉市江夏区神墩四路 666 号武汉国英种业大厦A栋14F 
邮箱:pinuofei2017@163.com
TEL:15392937510

IDH1 Polyclonal Antibody

复制产品信息

说明书下载
货号: PD2583
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: IDH1
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 46kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : IDH1 Polyclonal Antibody detects endogenous levels of IDH1 protein.
基因名称 : IDH1
蛋白名称 : Isocitrate dehydrogenase [NADP] cytoplasmic
别名 : IDH1;PICD;Isocitrate dehydrogenase [NADP] cytoplasmic;IDH;Cytosolic NADP-isocitrate dehydrogenase;IDP;NADP;+;-specific ICDH;Oxalosuccinate decarboxylase

数据库链接:

Organism

基因 ID

SwissProt

背景:

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to

细胞定位 : Cytoplasm, cytosol . Peroxisome .

推荐产品

相关文献

留言咨询

留下您想咨询的信息,我们会尽快联系您

提交