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货号: PD1088
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: DHE3
应用: WB
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 61kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : This antibody detects endogenous levels of DHE3 at Human/Mouse/Rat
基因名称 : GLUD1 GLUD
蛋白名称 : DHE3
背景:
This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. [provided by RefSeq, Jan 2016],


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