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CP46A Polyclonal Antibody

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说明书下载
货号: PG8526
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: CP46A
应用: WB,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 55kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;ELISA 1:5000-20000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : CP46A Polyclonal Antibody detects endogenous levels of protein.
基因名称 : CYP46A1 CYP46
蛋白名称 : Cholesterol 24-hydroxylase (CH24H) (Cytochrome P450 46A1)

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

cytochrome P450 family 46 subfamily A member 1(CYP46A1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008],

细胞定位 : Endoplasmic reticulum membrane ; Single-pass membrane protein . Microsome membrane ; Single-pass membrane protein . Cell junction, synapse, postsynapse . Cell junction, synapse, presynapse . Cell projection, dendrite .

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