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货号: PD2559
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
靶点: SERCA2
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat,Chicken
宿主物种 : Rabbit
MW(Observed): 115kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : SERCA2 Polyclonal Antibody detects endogenous levels of SERCA2 protein.
基因名称 : ATP2A2
蛋白名称 : Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
别名 : ATP2A2;ATP2B;Sarcoplasmic/endoplasmic reticulum calcium ATPase 2;SERCA2;SR Ca;2+;-ATPase 2;Calcium pump 2;Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform;Endoplasmic reticulum class 1/2 Ca;2+;ATPase
背景:
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2008],


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