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MDA-7 Polyclonal Antibody

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说明书下载
货号: PD2588
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: MDA-7
应用: WB,IHC,IF,ELISA
反应性 : Human,Rat,Mouse,
宿主物种 : Rabbit
MW(Observed): 24kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : MDA-7 Polyclonal Antibody detects endogenous levels of MDA-7 protein.
基因名称 : IL24
蛋白名称 : Interleukin-24
别名 : IL24;MDA7;ST16;Interleukin-24;IL-24;Melanoma differentiation-associated gene 7 protein;MDA-7;Suppression of tumorigenicity 16 protein

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],

细胞定位 : Secreted .

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