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CD166 Polyclonal Antibody

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说明书下载
货号: PD2602
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: CD166
应用: IF,WB,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 65kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : IF 1:50-200;WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications;
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : CD166 Polyclonal Antibody detects endogenous levels of CD166 protein.
基因名称 : ALCAM
蛋白名称 : CD166 antigen
别名 : ALCAM;MEMD;CD166 antigen;Activated leukocyte cell adhesion molecule;CD166

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2011],

细胞定位 : Cell membrane ; Single-pass type I membrane protein . Cell projection, axon . Cell projection, dendrite . Detected at the immunological synapse, i.e, at the contact zone between antigen-presenting dendritic cells and T-cells (PubMed:15294938, PubMed:16352806). Colocalizes with CD6 and the TCR/CD3 complex at the immunological synapse (PubMed:15294938). .; [Isoform 3]: Secreted .

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