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推荐稀释比 ： WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成 ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 ： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 ： -15°C to -25°C/1 year(Do not lower than -25°C
浓度 ： 1 mg/ml
克隆性 ： Polyclonal
抗原&靶点信息
特异性 ： Autotaxin Polyclonal Antibody detects endogenous levels of Autotaxin protein.
基因名称 ： ENPP2
蛋白名称 ： Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
别名 ： ENPP2;ATX;PDNP2;Ectonucleotide pyrophosphatase/phosphodiesterase family member 2;E-NPP 2;Autotaxin;Extracellular lysophospholipase D;LysoPLD
背景：
The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008],
细胞定位 ： Secreted .
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