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p57 Polyclonal Antibody

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说明书下载
货号: PD2650
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: p57
应用: WB,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 32kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;ELISA 1:20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : p57 Polyclonal Antibody detects endogenous levels of p57 protein.
基因名称 : CDKN1C
蛋白名称 : Cyclin-dependent kinase inhibitor 1C
别名 : CDKN1C;KIP2;Cyclin-dependent kinase inhibitor 1C;Cyclin-dependent kinase inhibitor p57;p57Kip2

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010],

细胞定位 : Nucleus .

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