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PEPCK-C Polyclonal Antibody

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说明书下载
货号: PD2732
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: PEPCK-C
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 65kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : PEPCK-C Polyclonal Antibody detects endogenous levels of PEPCK-C protein.
基因名称 : PCK1
蛋白名称 : Phosphoenolpyruvate carboxykinase cytosolic [GTP]
别名 : PCK1;PEPCK1;Phosphoenolpyruvate carboxykinase, cytosolic [GTP];PEPCK-C;Phosphoenolpyruvate carboxylase

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasm, cytosol . Endoplasmic reticulum . Phosphorylation at Ser-90 promotes translocation to the endoplasmic reticulum. .

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