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Fascin 1 Polyclonal Antibody

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说明书下载
货号: PD2755
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Fascin
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 55kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Fascin 1 Polyclonal Antibody detects endogenous levels of Fascin 1 protein.
基因名称 : FSCN1
蛋白名称 : Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55)
别名 : FSCN1;FAN1;HSN;SNL;Fascin;55 kDa actin-bundling protein;Singed-like protein;p55

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011],

细胞定位 : Cytoplasm, cytosol . Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, stress fiber . Cell projection, filopodium . Cell projection, invadopodium . Cell projection, microvillus . Cell junction . Colocalized with RUFY3 and F-actin at filipodia of the axonal growth cone. Colocalized with DBN1 and F-actin at the transitional domain of the axonal growth cone (By similarity). .

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