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XRCC1 Polyclonal Antibody

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说明书下载
货号: PD3012
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: XRCC1
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 70kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : XRCC1 Polyclonal Antibody detects endogenous levels of XRCC1 protein.
基因名称 : XRCC1
蛋白名称 : DNA repair protein XRCC1
别名 : XRCC1;DNA repair protein XRCC1;X-ray repair cross-complementing protein 1

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],

细胞定位 : Nucleus . Moves from the nucleoli to the global nuclear chromatin upon DNA damage. .

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