产品服务
信号通路
详细信息
推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : V-ATPase H Polyclonal Antibody detects endogenous levels of V-ATPase H protein.
基因名称 : ATP6V1H
蛋白名称 : V-type proton ATPase subunit H
别名 : ATP6V1H;CGI-11;V-type proton ATPase subunit H;V-ATPase subunit H;Nef-binding protein 1;NBP1;Protein VMA13 homolog;V-ATPase 50/57 kDa subunits;Vacuolar proton pump subunit H;Vacuolar proton pump subunit SFD
背景:
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The encoded protein is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATP but not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],


微信客服