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货号: PD3064
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
靶点: V-ATPase D
应用: WB,ELISA
反应性 : Human,Mouse,Rat,Swine
宿主物种 : Rabbit
MW(Observed): 28kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : V-ATPase D Polyclonal Antibody detects endogenous levels of V-ATPase D protein.
基因名称 : ATP6V1D
蛋白名称 : V-type proton ATPase subunit D
别名 : ATP6V1D;ATP6M;VATD;V-type proton ATPase subunit D;V-ATPase subunit D;V-ATPase 28 kDa accessory protein;Vacuolar proton pump subunit D
背景:
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein. [provided by RefSeq, Jul 2008],


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