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T-type Ca++ CP α1H Polyclonal Antibody

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说明书下载
货号: PD3149
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: T-type Ca++ CP α1H
应用: WB,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 259kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : T-type Ca++ CP α1H Polyclonal Antibody detects endogenous levels of T-type Ca++ CP α1H protein.
基因名称 : CACNA1H
蛋白名称 : Voltage-dependent T-type calcium channel subunit alpha-1H
别名 : CACNA1H;Voltage-dependent T-type calcium channel subunit alpha-1H;Low-voltage-activated calcium channel alpha1 3.2 subunit;Voltage-gated calcium channel subunit alpha Cav3.2

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

calcium voltage-gated channel subunit alpha1 H(CACNA1H) Homo sapiens This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). [provided by RefSeq, Jul 2008],

细胞定位 : Cell membrane ; Multi-pass membrane protein . Interaction with STAC increases expression at the cell membrane. .

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