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TTK Polyclonal Antibody

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说明书下载
货号: PD3150
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: TTK
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 100kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : TTK Polyclonal Antibody detects endogenous levels of TTK protein.
基因名称 : TTK
蛋白名称 : Dual specificity protein kinase TTK
别名 : TTK;MPS1;MPS1L1;Dual specificity protein kinase TTK;Phosphotyrosine picked threonine-protein kinase;PYT

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

TTK protein kinase(TTK) Homo sapiens This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009],

细胞定位 : kinetochore,cytoplasm,spindle,membrane,

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