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货号: PD3281
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: TGR5
应用: WB,ELISA,IHC
反应性 : Human,Rat,Mouse,
宿主物种 : Rabbit
MW(CalcμLated) : 35kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : TGR5 Polyclonal Antibody detects endogenous levels of TGR5 protein.
基因名称 : GPBAR1
蛋白名称 : G-protein coupled bile acid receptor 1
别名 : GPBAR1;TGR5;G-protein coupled bile acid receptor 1;G-protein coupled receptor GPCR19;hGPCR19;Membrane-type receptor for bile acids;M-BAR;hBG37;BG37
背景:
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],


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