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货号: PD3691
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: RNase Z2
应用: IHC,IF,ELISA
反应性 : Human,Rat,Mouse,
宿主物种 : Rabbit
MW(CalcμLated) : 92kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : RNase Z2 Polyclonal Antibody detects endogenous levels of RNase Z2 protein.
基因名称 : ELAC2
蛋白名称 : Zinc phosphodiesterase ELAC protein 2
别名 : ELAC2;HPC2;Zinc phosphodiesterase ELAC protein 2;ElaC homolog protein 2;Heredity prostate cancer protein 2;Ribonuclease Z 2;RNase Z 2;tRNA 3 endonuclease 2;tRNase Z 2
背景:
The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],


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