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Renin Polyclonal Antibody

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说明书下载
货号: PD3792
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Renin
应用: WB,IHC,IF,ELISA
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 40kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Renin Polyclonal Antibody detects endogenous levels of Renin protein.
基因名称 : REN
蛋白名称 : REN(Renin)
别名 : REN;Renin;Angiotensinogenase

数据库链接:

Organism

基因 ID

SwissProt

背景:

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008],

细胞定位 : Secreted. Membrane. Associated to membranes via binding to ATP6AP2.

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