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Rab11-FIP3 Polyclonal Antibody

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说明书下载
货号: PD3869
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Rab11-FIP3
应用: IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 82kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Rab11-FIP3 Polyclonal Antibody detects endogenous levels of Rab11-FIP3 protein.
基因名称 : RAB11FIP3
蛋白名称 : Rab11 family-interacting protein 3
别名 : RAB11FIP3;ARFO1;KIAA0665;Rab11 family-interacting protein 3;FIP3-Rab11;Rab11-FIP3;Arfophilin-1;EF hands-containing Rab-interacting protein;Eferin;MU-MB-17.148

数据库链接:

Organism

基因 ID

SwissProt

背景:

Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Mar 2008],

细胞定位 : Recycling endosome membrane ; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cleavage furrow . Midbody . In early mitosis remains diffuse and distributed through the cell. The onset of anaphase sequesters these vesicles to the centrosomes at the opposite poles of the cell. During telophase these vesicles move from the centrosomes, to the furrow, and then to the midbody to aid in abscission (PubMed:15158446, PubMed:15601896, PubMed:18511905). Interaction with Rab11 mediates localization to endosomes (PubMed:11495908). Interaction with ARF6 mediates localization to the midbody (PubMed:16148947). .

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