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货号: PD4691
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: Na+ CP type VIIα
应用: WB,IHC
反应性 : Human,Monkey
宿主物种 : Rabbit
MW(Observed): 200kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-2000;IHC 1:50-300
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : Na+ CP type VIIα Polyclonal Antibody detects endogenous levels of Na+ CP type VIIα protein.
基因名称 : SCN7A
蛋白名称 : Sodium channel protein type 7 subunit alpha
别名 : SCN7A;SCN6A;Sodium channel protein type 7 subunit alpha;Putative voltage-gated sodium channel subunit alpha Nax;Sodium channel protein cardiac and skeletal muscle subunit alpha;Sodium channel protein type VII subunit alpha
背景:
This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011],


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