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MMP-13 Polyclonal Antibody

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说明书下载
货号: PD4840
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: MMP-13
应用: WB,IHC,IF,ELISA
反应性 : Human,Rat,Mouse,
宿主物种 : Rabbit
MW(Observed): 60kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:100-300;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : MMP-13 Polyclonal Antibody detects endogenous levels of MMP-13 protein.
基因名称 : MMP13
蛋白名称 : Collagenase 3
别名 : MMP13;Collagenase 3;Matrix metalloproteinase-13;MMP-13

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016],

细胞定位 : Secreted, extracellular space, extracellular matrix . Secreted .

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