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推荐稀释比 ： WB 1:500-2000;IHC 1:50-300
组成 ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 ： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 ： -15°C to -25°C/1 year(Do not lower than -25°C
浓度 ： 1 mg/ml
克隆性 ： Polyclonal
抗原&靶点信息
特异性 ： MLTK Polyclonal Antibody detects endogenous levels of MLTK protein.
基因名称 ： MLTK
蛋白名称 ： Mitogen-activated protein kinase kinase kinase MLT
别名 ： MLTK;ZAK;HCCS4;Mitogen-activated protein kinase kinase kinase MLT;Human cervical cancer suppressor gene 4 protein;HCCS-4;Leucine zipper- and sterile alpha motif-containing kinase;MLK-like mitogen-activated protein triple kinase;Mixeed lineage kinase-related kinase;MLK-related kinase;MRK;Sterile alpha motif- and leucine zipper-containing kinase AZK;
背景：
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
细胞定位 ： Cytoplasm . Nucleus . Translocates to the nucleus upon ultraviolet B irradiation. .
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