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Mitofusin-2 Polyclonal Antibody

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说明书下载
货号: PD4892
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Mitofusin-2
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 86kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:100-300;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Mfn2 Polyclonal Antibody detects endogenous levels of Mfn2 protein.
基因名称 : MFN2
蛋白名称 : Mitofusin-2
别名 : MFN2;CPRP1;KIAA0214;Mitofusin-2;Transmembrane GTPase MFN2

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008],

细胞定位 : Mitochondrion outer membrane ; Multi-pass membrane protein . Colocalizes with BAX during apoptosis. .

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