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HLA-DOα Polyclonal Antibody

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说明书下载
货号: PD5343
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: HLA-DOα
应用: WB,IHC,IF,ELISA
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 34kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : HLA-DOα Polyclonal Antibody detects endogenous levels of HLA-DOα protein.
基因名称 : HLA-DOA
蛋白名称 : HLA class II histocompatibility antigen DO alpha chain
别名 : HLA-DOA;HLA-DNA;HLA-DZA;HLA class II histocompatibility antigen;DO alpha chain;MHC DN-alpha;MHC DZ alpha;MHC class II antigen DOA

数据库链接:

Organism

基因 ID

SwissProt

背景:

HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq, Jul 2008],

细胞定位 : Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Complexes with HLA-DM molecule during intracellular transport and in endosomal/lysosomal compartments. Heterotetramerization is necessary to exit the ER.

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